Nitrazepam 5 mg & 10 mg
As the patent expired so many years ago, generic versions of Nitrazepam have been available for a long period of time. Some of the pharmaceutical companies in the UK that manufacture this medication include Actavis and Accord. Many people prefer to buy Nitrazepam in its generic form as opposed to branded versions, as generic medication is available at a fraction of the cost.
Are you looking for more information about how this medication functions? Maybe you are looking for an affordable treatment than the high street cannot offer? Do you want a medication that effectively treats your symptoms? We have a lot more information for you and as you keep reading, we are sure we will answer any questions you may have.
What is Nitrazepam Used to Treat?
Nitrazepam pills are licenced to treat severe sleep disorders. They are also used off-label for the management of severe anxiety when the symptoms cause significant distress. When a medication is used off-label, it is still agreed by medical professionals to be effective for that cause. There are other, less common Nitrazepam uses which include the treatment of some types of seizures, to induce amnesia, and it can be used as a muscle relaxant.
Sleep problems are the main indication for this medication. The different of insomnia include:
- Sleep-onset- this is when a person finds it hard to drift off to sleep. It can take up to an hour, but it may take several hours to fall asleep for some people. This type of insomnia can be acute, which means it lasts for a short period of time, or it may be chronic, which means it lasts for longer than 3 months.
- Sleep maintenance- this is when a person can easily drift off to sleep, but they find that they wake up in the night. When they wake up in the middle of the night, they find it hard to get back to sleep again. For others, it may be that they wake up too early despite the amount of sleep they have had. This type can also be acute or chronic and is more difficult to treat than sleep-onset insomnia.
People also used Nitrazepam for anxiety when it causes debilitating symptoms. It is usually used on a short-term basis and more commonly for anxiety-induced sleep disorders as opposed to conditions such as general anxiety disorder for example.
Nitrazepam Mechanism of Action
The Nitrazepam mechanism of action almost mirrors other benzodiazepines, which work as central nervous system (CNS) depressants. The CNS is a complex system that regulates everything that happens in the body. Sometimes an imbalance of our natural chemicals can cause disorders, including insomnia and anxiety. Benzodiazepines all have a similar chemical structure, and they interact with benzodiazepine receptors in the brain, which are associated with gamma-aminobutyric acid () receptors.
When the Nitrazepam active ingredient bind to the benzodiazepine receptors, it enhances binding to GABA receptors. GABA receptors are found in abundance in the CNS and brain. Upon binding, the GABA receptors produce a neurotransmitter, which is a type of regulatory chemical, also called GABA. As mentioned, this is a CNS depressant, which means it causes a reduction in some of the signals in the brain associated with insomnia and anxiety. This is a powerful sedative-hypnotic and when you have taken it you will benefit from its calming and sedating effects.
Nitrazepam Duration of Action
Nitrazepam is effectively absorbed after ingesting it. It travels from the stomach to the intestines, where it is partly metabolised then enters the bloodstream, where it then crosses the blood-brain barrier where it can bind to receptors. The bioavailability of this medication is 53-94% so it can vary from person to person. It has a quick onset of action, and you will feel the Nitrazepam benefits after 30 to 60 minutes, and peak concentrations are reached after 2 hours.
Both the bioavailability and the onset of action are dependent on how your body works, for example, how fast or slow your metabolism works. Whether you take this medication with or without food has no bearing on the bioavailability or absorption of the medication. The Nitrazepam duration of action is much longer than other medications which belong to the benzodiazepine family.
It has an elimination half-life of 26 hours on average, so if you are taking it daily, for severe anxiousness, for example, it will take about 5 days to reach a steady level in your system. The long duration of action is perfect for both sleep-onset and sleep-maintenance insomnia and will allow you to get 6 to 8 hours of uninterrupted sleep.
Dosage Instructions for Nitrazepam
Prior to starting treatment, it is essential that you carefully read the Nitrazepam dosage instructions. This is so that you can get the best possible results from your treatment. There are two strengths of this medication available. Nitrazepam 5 mg is the lower dose, and an ideal starting dose for most people. If you have moderate sleep issues, then this could also be the maintenance dose. Nitrazepam 10 mg is used if the lower strength is not effective enough and for more severe insomnia and anxiety. If you are taking the lower dose, you can always break the 10 mg tablet in half to achieve your desired strength.
Your dosage schedule will depend on whether you are using it for insomnia or anxiety. For sleeping problems, take it about 30 minutes before bedtime. Try to take it at the same time each night for continuity and to maintain good sleep hygiene. For anxiety, take your medication once in the morning and once at teatime. You may not need to take it every day, this will depend on the severity of your symptoms.
Always store your medication out of sight and out of reach of children. It should ideally be kept in a locked drawer or cabinet to prevent children from getting to it. Additionally, to keep your medication at its most potent, it should be kept out of direct sunlight in a cool and dry place.
Does Nitrazepam Have Side Effects?
Every medication can cause side effects and before you buy Nitrazepam online you should familiarise yourself with any that may arise. A lot of people tolerate this medication well and side effects affect a relatively small number of people. Common Nitrazepam side effects include:
- Feeling unsteady
- Reduced alertness
As the Nitrazepam elimination half-life is so long, it is very common for people to feel drowsy or less alert the following day. This means that it is important to avoid driving or performing complex tasks. If you experience a headache when you take this medication then you can take over the counter painkillers such as paracetamol, as well as ensuring you stay well hydrated.
It is incredibly rare, but a small number of people who take this medication may have serious adverse effects. Serious Nitrazepam side effects include:
- Trouble breathing
- Severe mood swings
- Urinary retention
If any of these serious adverse effects occur, seek immediate medical assistance, and stop taking the medication. This is not a full list of potential side effects, and if you would like more information, then you can read the patient information leaflet which contains the full list of Nitrazepam side effects. This information is available on our site.
Can Nitrazepam Be Used Long Term?
Nitrazepam 10 mg should ideally be taken intermittently and for no longer than 28 days without a break from taking it. This medication can cause physical dependence, which means that when you stop taking it after 28 days, you may suffer from withdrawal effects. It is important that you taper off the medication if you have been taking it for a long time to reduce these unpleasant effects. Another reason it should be taken intermittently is that your tolerance will increase further, the longer you take Nitrazepam tablets. Increased tolerance means that your body has adjusted to the medication, and it is, therefore, less effective than when you first started taking it.
There are other methods you can implement to improve your sleeping pattern. Good sleep hygiene is essential for maintaining a healthy sleep schedule. Sleep hygiene includes going to bed and getting up at the same time each day, making sure you have a good sleep environment such as a dark room that is not too hot or too cold, not drinking caffeine before bed, and not looking at blue screens before bed. By implementing these measures, you can gradually reduce your Nitrazepam dosage until it is no longer required and you can overcome your difficulties with sleeping.
Should Anyone Avoid Nitrazepam
Although this is a safe medication for most people to take, you should tell your doctor if any of the following apply to you before you buy Nitrazepam:
- You have an allergy to Nitrazepam or any of the ingredients listed
- You have liver or kidney disease
- You have myasthenia gravis
- You are taking benzodiazepines such as Lorazepam
- You are taking non-benzodiazepines such as Zolpidem
- You are taking opioid-based medications such as morphine
- You have addiction problems
This is not a full list of conditions or medications which could interact with this one. If you are unsure whether you can take this medication safely or not, speak to a qualified health professional before taking this or any other medication.
Considerations Before You Buy Nitrazepam
Medication is available from a wide variety of outlets, including from high street stores, chemists, and online pharmacies. Unless you have a prescription, medication you can get from high street stores or chemists are not as strong and many people find that they are not effective enough for their needs. Options are also limited and can vary due to reasons such as stock levels or the variety of medication sold.
People tend to prefer to buy Nitrazepam online as it offers more benefits. Our medication is all available without a prescription and it is more affordable than high street medications. You will also have much more privacy when you shop with us, as you will not need to interact with anyone, and your Nitrazepam will be posted to you in a plain envelope.
Where to Buy Nitrazepam in the UK
And there you have it, all the information required to help you purchase this medication with full confidence. Placing your order is a simple process and takes next to no time at all, from start to finish. The first thing you need to do is decide on the product that you want to buy. When you have decided on a product, and arrived at the product page, for example, Nitrazepam 10 mg, you can select the number of tablets you wish to order. When you have selected this, you can add them to your cart and proceed to the checkout.
When you reach the checkout section there will be instructions on how to complete the transaction. You can make a payment using a Visa, Mastercard, bank transfer, or even Bitcoin. After you have made your payment, you will get an email shortly after that will confirm that it has been received. It will also tell you the name that will appear on your payment statement, and the estimated delivery date. UK to UK delivery is fast and you should receive your order in as little as 2 days. UK to EU delivery will take approximately 4 to 7 days.
Place your order and buy Nitrazepam at Sleeping Tablets Direct to get the restful nights sleep that you deserve.
FAQ - Nitrazepam
What is Nitrazepam Used for?
Nitrazepam is used for the short-term treatment of sleeping problems, including difficulty falling asleep, frequent awakenings and early morning awakening. Nitrazepam works by targeting certain chemicals in the brain which reduce anxiety helping you to fall asleep and stay asleep.
Is Nitrazepam Stronger than Diazepam?
Yes, Nitrazepam shows stronger sedative effects than Diazepam making it more suitable as a sleep aid medication. Simply put Diazepam is an anxiety medication that helps with sleep whereas Nitrazepam is a sleep medication that helps with anxiety.
What are the Effects of Nitrazepam?
Nitrazepam works by targeting the neurotransmitters in the brain and induces a feeling of calmness, relaxation and euphoria. The effects of Nitrazepam lead to reduced anxiety and increased tiredness.
Does Nitrazepam Help You Sleep?
Nitrazepam is a trusted medication when it comes to sleeping disorders and yes it will help you sleep. One Nitrazepam 10mg tablet 30 - 60 minutes before going to bed will ensure a good night's sleep.
How Much does Nitrazepam Cost?
The price of Nitrazepam starts from approximately £1.00 per pill. The more you buy the cheaper it gets and when you buy in larger bulk orders you can pay as little as £0.80 per pill.
Last Reviewed: 28/06/22
While this medication may be consumed with or without food, it is not recommended that patients consume it on a completely empty stomach. Likewise, the effects of this medication will be dulled, or seem weaker, if taken on a full stomach, or after eating a heavy meal.
This Medication Should:
- be consumed in accordance with the patient information leaflet.
- be swallowed whole; do not crush, chew or suck these tablets / capsules.
- be stored in a cool dry place / at room temperature (20°C - 25°C).
- be kept out of the reach of children at all times (minors under the age of 18).
This Medication Should Not
- be mixed with alcohol - even one drink can be dangerous.
- be used if pregnant, breastfeeding (or planning to become pregnant).
- be shared - even with friends or family experiencing symptoms similar to yours.
- be taken when planning to drive or operate dangerous machinery.
NOTE: If you, or anyone you know, have taken too much of this medication, or if you are experiencing any unwanted side-effects such as a rash, difficulty breathing or swelling of any kind, you should contact a doctor immediately.